Exosomes & Extracellular Vesicles
Boost EV yield and cargo quality with 3D dynamic culture, a scalable route to therapeutic vesicle and exosome production.
Extracellular vesicles (exosomes) from MSCs and other cells are emerging as therapeutics and drug-delivery vehicles. Vertical-Wheel® 3D dynamic culture enhances EV secretion and cargo profile versus planar culture, opening a path to scalable EV manufacturing.
3D aggregate and microcarrier culture in dynamic conditions upregulates EV secretion relative to static planar culture.
Bioreactor conditions enhance the therapeutic cargo and proteomic profile of secreted vesicles.
A clear path from bench development to large-scale therapeutic EV manufacturing.
What You Can Build.
Workflows our customers and collaborators run on the Vertical-Wheel® platform, every one backed by published data or a protocol below.
- MSC-derived EVs
- NK-derived EVs
- Organoid-derived exosomes
- EV manufacturing
- Drug-delivery vesicles
Upscaling hMSC production in a Vertical-Wheel® bioreactor enhanced extracellular-vesicle secretion and improved cargo profile versus planar culture.
The Evidence for EVs.
Application notes, protocols and peer-reviewed data with tangible results in Vertical-Wheel® bioreactors, leading with the studies that show real numbers.
No documents are tagged for this cell type yet.
Ready to Scale Your EVs Process?
Talk to an application scientist about a Vertical-Wheel® path tuned to your cell type and timeline.