Cell Therapy, Scaled Up.
Proof at Every Scale.
Produced in a single PBS-80 run, expanded linearly from the benchtop.
Read the study11Clinical programsRunning on the platform today, including three customers in Phase 3.
Explore the evidence0.1 → 50 LhMSC scale-uphMSCs scaled in a xeno-free process, preserving CQAs and potency.
Read the app noteGo Vertical and Make Your Process Simple.
PBS Biotech provides a complete cell therapy manufacturing platform: scalable bioreactor systems, a controlled cell growth environment, and the support to make scaling your process predictable.
A Paradigm Shift from Stir-Tank Bioreactors.
Energy spreads evenly across the whole vessel. There are no high- and low-shear zones, and none of the turbulent bands a stirred tank produces.
A scalable impeller-to-vessel ratio keeps the mixing environment identical as vessels grow, all the way to commercial volumes.
Homogeneous EDR gives predictable control over aggregate size and downstream differentiation, and the same mechanical energy can dissociate aggregates directly in the vessel, no separate step required.
One Platform. Five Scales.
Every system shares the same wheel geometry, the same single-use vessel family and the same control language. Move up when your program is ready.
Find the Process Behind Your Cells.
Published runs, seeding densities and scale-up data, grouped by what you are growing.
Your Partner from Start to Scale.
A Vertical-Wheel® system comes with a process-development team, not just hardware. Our programs de-risk each transition on the way from feasibility run to commercial supply.
Start with a Conversation.
Book a thirty-minute introduction with a member of our team. We walk you through the Vertical-Wheel® platform and the technology behind it, answer your questions, and talk through your process and where it is headed.