MSCs
Mesenchymal Stem / Stromal Cells
Scalable, xeno-free MSC manufacturing on microcarriers or aggregates, from flasks to 80 L, with extracellular-vesicle potential built in.
0.1–50 L
demonstrated scales
Xeno-free
fed-batch process
↑ EV
secretion vs planar
Why Vertical-Wheel
Built For This Cell Type.
Gentle on shear-sensitive cells
Uniform low-shear mixing protects hMSC viability and phenotype while keeping microcarriers or aggregates suspended.
Microcarrier-optimized
Even microcarrier suspension, including customizable and dissolvable options that improve harvest and direct visualization.
Fed-batch productivity
Xeno-free fed-batch processes lift final cell yields and EV cargo across 0.1 L to 50 L scales.
Applications
- BM-MSC expansion
- Cord-blood MSC
- Adipose-derived MSC
- Microcarrier culture
- Fed-batch processes
- MSC-derived EVs
Systems for This Cell Type
Each system carries the note explaining why it suits this cell type.
- PBS-MiniProcess & microcarrier optimization
- PBS-3Microcarrier GMP-readiness
- PBS-15Clinical-scale capacity
- PBS-80Commercial (demonstrated to 50 L)
0.1–50 L
A xeno-free hMSC process maintained critical quality attributes across 0.1 L, 3 L, 15 L and 50 L Vertical-Wheel® scales.
Evidence
The Data Behind It.
Talk Through Your Process.
Our scientists work on these processes daily. Bring us your cell type, your scale and your constraints.