PBS Biotech
Organoids & Islets

Organoids, Embryoids & SC-Islets

Generate uniform aggregates, embryoids and organoids at scale, from pancreatic islets to brain, liver and blood-vessel models, with the size control that drives consistent differentiation.
Faster
commitment vs static
5 cell types
in mature cerebellar organoids
Brain · retina · liver
organoid models
Why Vertical-Wheel

Built For This Cell Type.

Size uniformity

Homogeneous mixing yields narrow aggregate and organoid size distributions, the critical quality attribute for reproducible, efficient differentiation.

Gentle yet well-mixed

A rare combination of low shear for high viability with effective dispersion, so growth factors and cytokines diffuse uniformly through every organoid.

Scalable differentiation

Multi-week protocols run start-to-finish in suspension and scale linearly: a 5× volume increase delivered 12× more islets with no quality compromise.

Applications

  • SC-islets (diabetes)
  • Liver organoids
  • Brain & cerebellar organoids
  • Retinal organoids
  • Blood-vessel organoids
  • Embryoids / EBs
  • Disease modeling
  • Drug & tox screening

Systems for This Cell Type

Each system carries the note explaining why it suits this cell type.

  • PBS-MiniOrganoid, embryoid & islet development
  • PBS-MiniPROParallel differentiation screening
  • PBS-3Scaled differentiation (GMP runs)
  • PBS-15Larger organoid batches
  • PBS-80Differentiation demonstrated to 50 L
Faster

Transcriptome profiling of hPSC-derived cerebellar organoids found that dynamic Vertical-Wheel® culture accelerated cerebellar commitment against static controls, with better extracellular-matrix organisation and multiple cerebellar neuronal populations forming.

Silva et al., 2021
Evidence

The Data Behind It.

All resources

No documents are tagged for this cell type yet.

Talk Through Your Process.

Our scientists work on these processes daily. Bring us your cell type, your scale and your constraints.