About PBS Biotech

Accelerating Therapies from Start to Scale

PBS Biotech develops scalable, single-use bioreactor systems and process-development expertise that help cell & gene therapy developers move from R&D to clinical and commercial manufacturing with greater confidence, powered by proprietary Vertical-Wheel® Technology.

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Recognition & Readiness

Trusted for the Journey to the Clinic

Industry Recognized

Named 2025 Bioreactor of the Year and 2026 Cell Products Development of the Year.

NPS 80 Customer Satisfaction

A Net Promoter Score of 80 reflects deep trust from the developers who scale on our platform.

cGMP-Ready & 21 CFR Part 11

Systems and single-use vessels built to support the transition into compliant clinical and commercial manufacturing.

Our Story

We Built the Platform Cell Therapy Was Missing

01We saw the bottleneck.

Cell therapy was moving from academic breakthroughs to life-altering cures made at scale — and manufacturing was the bottleneck. We positioned ourselves to solve it.

02We built for cells’ unique needs.

Cells need gentle, homogeneous mixing that stirred tanks can’t give. The Vertical-Wheel platform holds that mixing environment constant from 0.1 L to 80 L.

03Our mission goes beyond hardware.

We provide not just the technology but the support and services teams need to navigate this new, uncertain field. That is our mission.

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See PBS Biotech in Action

A closer look at how the Vertical-Wheel platform gently scales cell & gene therapies from bench to commercial, and the team behind it.

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What We Do

Three Ways We Accelerate You

Technology

Proprietary Vertical-Wheel mixing: gentle, homogeneous and linearly scalable across every working volume, in five systems from 0.1 L to 80 L.

How it works →Support

Application scientists, field engineers and technical support behind every system you run — installation, training and troubleshooting.

Get support →Services

Process development, scale-up characterization and tech transfer run alongside your team, in our lab or yours.

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Customer Success Story

In Their Own Words

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“We’ve had great success expanding iPSCs at Roslin in the Vertical-Wheel bioreactor, thanks to the wonderful support and products we receive from PBS Biotech. Training and installation of the 3-liter system were superb. We were able to culture iPSCs in the 3-liter system using PBS’s perfusion kit, demonstrating end-to-end iPSC manufacture in a completely closed system at this scale.”

Barbara ResslerVP Process Sciences, Roslin CT

Leadership

The Team Behind the Platform

Twenty-plus years each in biopharmaceutical development, bioprocessing, global operations and commercial leadership — from Amgen, Merck, Genentech, Thermo Fisher and Danaher.

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Martin Simonetti

Chief Executive Officer

A veteran biotech executive and board advisor with a track record of financial and operational leadership at VLST, Dendreon, Amgen and Genentech, and deep experience guiding strategic growth across the life sciences.

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Brian Lee, Ph.D.

CTO and Founder

Over 25 years of research and leadership experience in biopharmaceutical R&D, bioprocess scale-up and biomanufacturing with Amgen and Merck.

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Erik Wiberg, MBA

Chief Financial Officer

Over 25 years of finance leadership in life-science tools and capital equipment, including Thermo Fisher Scientific, Gyros Protein Technologies and Resolve Biosciences.

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Terrell Mathews

Chief Commercial Officer

Over 20 years in sales and marketing, formerly executive Vice President of Global Sales at Danaher's Molecular Devices and Phenomenex.

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Joe Petrosky

Sr. VP of Global Sales

Over 25 years of sales and customer management experience with biotech and medical products at Charter Medical and Millipore Corporation.

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Mark Schneider

Senior VP of Finance & Controller

Over 25 years of accounting and financial management experience in biopharmaceutical companies including Amgen, Kythera and Sienna.

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Peter Kim

VP of Operations

Board of Directors

Brian Lee, Ph.D.Chairman of the Board, CTO and Founder of PBS Biotech.

Dennis Fenton, Ph.D.Former Executive VP at Amgen.

Leland Foster, Ph.D.Former CEO of Fisher Scientific Biosciences and Chief Scientist at Thermo Fisher Scientific.

Jerry LiaoPrincipal at Avego Management.

Daniel FriedmanManaging Director at BroadOak Capital Partners.

Advisory Board

Matthew Croughan, Ph.D.Over 35 years of bioprocessing experience as former CTO of Sapphire, Director of the Amgen Bioprocessing Center at KGI, and Chief Scientist at Genentech.

Steve LamFormer VP and General Manager of Single-Use Technology at Thermo Fisher Scientific and VP of Operations at Amgen.

Susan LundeenFormer VP of Human Resources at Amgen and Kythera Biopharmaceuticals.

Bryan PoltiloveFormer Operating Partner at BroadOak Capital and former VP at Thermo Fisher Scientific.

Bill RichFormer VP of Device Technologies, VP of External Supply and VP of International Supply Chain at Amgen.

Careers

Build the Future of Manufacturing

We’re a team of engineers, scientists and problem-solvers in Camarillo, California, working at the intersection of bioprocessing and cell therapy. If making therapies scalable excites you, we’d love to meet you.

Careers at PBS Biotech

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Commitment to Quality

Built to Carry Your Process Into the Clinic

Every system, vessel and service we deliver is governed by one quality system, because the process you validate on our hardware has to hold up under audit.

ISO-certified quality system

Design, manufacturing, service and document control all run under one certified quality management system.

21 CFR Part 11 support

Control software and records are built to support Part 11 compliant electronic records and signatures in regulated production.

Controlled-environment manufacturing

Single-use vessels are produced and packaged under clean-room controls, then released against documented specifications.

A dedicated quality organization

A standing QA/QC team owns supplier qualification, incoming inspection, CAPA and change control, and supports your audits.

Certificates, quality manuals and audit documentation are available on request.

How Can We Help?

Tell us what you need and we’ll take it from there.