One Platform. Bench to Commercial.
Five single-use systems that share the same gentle Vertical-Wheel® mixing, so a process you develop at 0.1 L transfers predictably to 80 L. Every system runs a pre-sterilized single-use vessel.
Find Where You Are.
Select a stage to jump to the system built for it. The same mixing physics runs through all five.
Benchtop Vertical-Wheel® vessels to prove feasibility and dial in your process at minimal cost and risk: a true scale-down model for everything above it.
All Five Systems at a Glance.
| System | Working volume | Vessel | cGMP | OPC-UA | Best for |
|---|---|---|---|---|---|
| PBS-Mini | 0.1–0.5 L | Vertical-Wheel® 0.1 L and 0.5 L | – | Early R&D & feasibility screening | |
| PBS MiniPRO | up to 0.5 L | Vertical-Wheel® 0.5 L | DoE, media & feed optimization | ||
| PBS-3 | 1.8–3 L | Vertical-Wheel® 3 L | Tech transfer & GMP preparation | ||
| PBS-15 | 10–15 L | Vertical-Wheel® 15 L | Clinical batch capacity | ||
| PBS-80 | 40–80 L | Vertical-Wheel® 80 L | Soon | Commercial allogeneic supply |
The Purpose-Built Home for Your Cells.
Every Vertical-Wheel® system runs a pre-sterilized, single-use vessel, keeping your culture closed and contamination-free, with the same wheel geometry from 0.1 L to 80 L. Nothing to clean or re-validate between runs.
Consistent geometry across every scale: the mechanism your cells experience never changes.
Closed & single-use: reduces contamination risk and eliminates cleaning validation.
Sized for every system: Vertical-Wheel 0.1 L, 0.5 L, PRO, 3 L, 15 L and 80 L.
Turn the Bioreactor in Your Hands.
Drag to orbit, scroll to zoom, double-click to focus. A viewer like this on each product page lets a process engineer inspect port placement, wheel geometry and the drive head without a site visit or a CAD license.
Every angle, on any device: works on desktop and touch, no plugin.
Annotated hotspots can label ports, sensors and the impeller in the final version.
One model per system: PBS-Mini through PBS-80, published from your existing CAD.
Everything Around the Vessel.
Computer-controlled system for running up to 24 vessels at once. View the brochure.
Closed-system sampling for representative in-process measurements. View the brochure.
Order vessels, media accessories and consumables directly from the PBS Biotech shop.
Get Onto the Platform Faster.
Bundles, starter packs and credit redemption make it easier to start and scale.
Every $1 spent on PBS-Mini products earns 1 credit toward your next step up the ladder.
Open the calculator →Success BundlesGuided OptimizationConsulting packages that accelerate your progression from R&D to clinical scale.
Learn more →Starter PacksJump-Start Your ProcessCurated PBS-Mini kits paired with a discounted Success Bundle.
Get started →See Your Set Points at Every Scale.
Because Vertical-Wheel® scale-up is genuinely linear, one working volume and agitation rate map cleanly to every larger system. Enter yours and get the equivalent set points from PBS-Mini to PBS-80, the same CFD-validated hydrodynamic conditions at each step.
Open the Scale-Up CalculatorNot Sure Which System You Need?
Tell us your cell type and timeline. We'll map the right scale-up path.