PBS Biotech
Cardiac Cells

Cardiomyocytes

Produce ventricular and atrial cardiomyocytes from pluripotent stem cells in suspension, expansion through differentiation in one system.
500 mL
demonstrated scale
2 subtypes
ventricular and atrial
One system
expansion to differentiation
Why Vertical-Wheel

Built For This Cell Type.

One vessel, end to end

Expansion, mesoderm induction and differentiation run in the same bioreactor, removing the transfers that cost yield and add contamination risk.

Both cardiac subtypes

The growth-factor-based process yields ventricular and atrial cardiomyocytes rather than a single lineage.

Function validated, not inferred

Cells were characterised by electrophysiology, force generation and transplantation studies rather than by marker expression alone.

Applications

  • Directed differentiation
  • Aggregate culture
  • hiPSC / PSC expansion
  • Disease modeling
  • Drug & tox screening

Systems for This Cell Type

Each system carries the note explaining why it suits this cell type.

  • PBS-MiniDifferentiation process development
  • PBS-MiniPROScale-up to 500 mL (demonstrated)
500 mL

A growth-factor-based process produced ventricular and atrial cardiomyocytes from human pluripotent stem cells in Vertical-Wheel® bioreactors, integrating expansion, mesoderm induction and differentiation, scaling to 500 mL, with function validated by electrophysiology, force generation and transplantation.

Alibhai et al., 2025
Evidence

The Data Behind It.

All resources

No documents are tagged for this cell type yet.

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Our scientists work on these processes daily. Bring us your cell type, your scale and your constraints.